The device functions by measuring the blood flow in 22 joints of the wrists and hands using diffuse optical transmission in combination with a patented blood circulation modulation method. Predicated on optical technology the device poses no risk for the patient and can be fast, operator independent, easy and inexpensive to use. The technology is not related to Philips primary imaging modalities and patient monitoring solutions. Dr. Wouter Dr and Rensen. Michiel van Beek, co-founders of Akeso, developed and invented the RA optical swelling detection technology inside Philips Research. Dr. Regular objective monitoring of swelling allows for fine-tuning of the treating RA, leading to earlier remission, fewer inflammatory episodes and much less pain for individuals, in the long run reducing functional loss and lowering health care costs and economic losses.Published in The Journal of Discomfort, the guidelines state that prescribers of opioid pain drugs must have clinical abilities and understanding in both the principles of opioid treatment and the assessment and management of dangers associated with drug abuse, addiction and diversion. According the APS-AAPM recommendations, before prescribing an opioid medication, the physician must carry out a thorough health background and assess and examination potential risk for drug abuse, misuse or addiction. The strongest predictor of possible medication misuse is a personal history of alcoholic beverages and drug abuse. For individuals at higher risk for drug misuse, doctors must definitely provide more structured treatment that can include more frequent visits highly, regular urine drug displays, regular contact with family members, smaller prescriptions, pill counts, counseling, or various other interventions.