A dark mole with a woolly border The woolly border seen on dermoscopy of blue naevi is because of the current presence of deeply pigmented spindle melanocytes blending with the encompassing skin within the dermis. Case presentation An 18-year-older man noticed a dark mole on his spine , six months to consultation prior. He sensed that the intensely pigmented mole had grown gradually in the interval. Excision biopsy revealed a dermal infiltrate of pigmented spindle-formed melanocytes deeply, which extended into the encircling dermis but lacked nuclear atypia or mitoses ..Based on the National Institutes of Wellness, there are several types of SMA, and life expectancy depends on how the disease impacts breathing. There is absolutely no cure, but medicines and physical therapy help deal with symptoms. Beattie and co-workers began this line of work in the past after a clinician compared the bloodstream of siblings – one with slight spinal muscular atrophy and one who was unaffected – and discovered that the unaffected child’s plastin 3 levels were higher than those in the sibling with SMA. Related StoriesResearchers effectively repair nerve cell damage in Alzheimer's dementiaProtein sensor for proprioception foundGriffith University uncovers initial 3-D image of protein linked to cancer spreadThe Ohio Condition researchers are employing animal studies to pinpoint the role of plastin 3 in this disease, and how it pertains to SMN specifically, the protein regarded as lacking in children with spinal muscular atrophy.