The hallmark of physiological exhaustion is reversal with short cessation or decrease in training. In contrast, pathological fatigue is persistent and outcomes in impaired performance. This article discusses common causes of persistent fatigue in presents and athletes a practical approach to management.. A practical approach to persistent fatigue in athletes Fatigue in sports athletes is a common presentation in general practice. Persistent exhaustion is usually suggestive of inadequate recovery but might signal an fundamental medical cause also. Fatigue in athletes can be a common presentation generally practice.The pharmacy sector, actually, has been a leader in wellness IT with its use of digital prescribing and has very much to offer the broader healthcare industry as it develops digital systems that improve effectiveness while ensuring patient basic safety and privacy. AMCP, for example, has worked with pharmacy stakeholders to build up e-prescribing criteria and continues to function closely with industry to greatly help improve pharmacists’ capability to offer medication therapy management through the use of standardized coding.