Neurons ofptides.

Neurons rate can be the key to preventing obesityResearchers have discovered how a hormone produced in the gut, the rate of gastric emptying with and thus suppresses appetite and food intake slows down. Results of animal studies have been at the Endocrine Society ‘s 94th Annual Conference in Houston presented. – The gut hormone glucagon-like peptide 2 or GLP-2 acts through a neurotransmitter and tweaking gastric emptying – as suspected – its receptor action in the brain, said study leader, Xinfu Guan, Assistant Professor of Pediatrics and Medicine at Baylor College of Medicine in Houston.

This results, Guan, that takes place in the central nervous system, the GLP-2 receptor is an important physiological role in the control of food intake, and the gastric emptying.

The researchers also found that this receptor rapidly PI3K PI3K intracellular signaling in the POMC neurons. This in turn induces neuronal excitation and gene expression after Guan.

‘This study our understanding of the brain-gut neural circuits that mediate the eating behavior advanced through modulating gastric emptying, which helps to control of body weight,’he said.TITLE: Cardiac mast cells run atrial fibrillation by PDGF-A -mediated fibrosis at Print overburdened mouse hearts.. Detected to immune cells are known than mast cell into Afib.

Initial analysis demonstrated that the mouse model of atrial fibrillation, and mast cells accumulation become in the auricles of the heart, atrial atrial fibrosis and intensified susceptibility to the inducing from atrial fibrillation thereby. Stabilized mast cells and mast cells mice deficient producing reducing fibrotic atrial remodeling and vulnerability to AF induction.