Discovered ,, ABCA1 is a naturally occurring enzyme already under study for their potential to treat heart conditions tadalafil 20 mg . Lipids like cholesterol are insoluble in order through the bloodstream and into and out of cells and organs , they must be labeled molecules can be transported as apolipoproteins associated. ABCA1 facilitates this process, the known as lipidation is.
Holtzman perform additional studies to clarify the details of the relationship between ABCA1, apoE and amyloid beta.Wahrle SE, Jiang H, Parsadanian M, Node A, Hirsch – Reinshagen V, Wellington CL, Bales KR, Paul SM, Holtzman DM Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer ‘s disease. Journal of Clinical Investigation, February 2008 .
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